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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP4
All Species:
34.85
Human Site:
Y225
Identified Species:
54.76
UniProt:
Q02790
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02790
NP_002005.1
459
51805
Y225
I
V
Y
L
K
P
S
Y
A
F
G
S
V
G
K
Chimpanzee
Pan troglodytes
XP_508927
414
47057
K209
L
H
L
K
S
F
E
K
A
K
E
S
W
E
M
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
Y225
I
V
Y
L
K
P
S
Y
A
F
G
S
V
G
K
Dog
Lupus familis
XP_534923
459
51500
Y225
I
V
Y
L
K
P
S
Y
A
F
G
S
V
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P30416
458
51554
Y225
I
V
Y
L
K
P
S
Y
A
F
G
S
V
G
K
Rat
Rattus norvegicus
Q9QVC8
458
51432
Y225
I
V
Y
L
K
P
S
Y
A
F
G
S
V
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
L214
K
L
I
Y
E
V
T
L
K
S
F
E
K
A
K
Chicken
Gallus gallus
NP_001006250
442
50413
Y218
I
F
Y
L
K
P
N
Y
G
F
G
S
T
G
K
Frog
Xenopus laevis
NP_001084916
447
50310
Y221
V
L
Y
L
K
P
K
Y
G
F
S
M
T
G
S
Zebra Danio
Brachydanio rerio
NP_958877
449
50474
Y220
L
F
T
I
K
P
K
Y
G
F
G
T
A
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
N222
E
E
F
K
I
P
P
N
A
T
V
E
Y
T
V
Honey Bee
Apis mellifera
XP_395748
459
51510
A222
E
F
D
I
P
P
N
A
T
V
E
Y
I
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
I213
G
I
V
E
G
L
E
I
A
I
K
R
M
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
Y225
I
V
Y
L
K
P
S
Y
A
F
G
S
V
G
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
Y230
L
L
T
V
K
P
Q
Y
G
F
G
E
K
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
98.4
91.7
N.A.
89.7
89.9
N.A.
46.4
74.7
66
61.2
N.A.
41.3
47.7
N.A.
45.9
Protein Similarity:
100
90.1
99.5
97.5
N.A.
95.4
95.2
N.A.
65.3
86
80.6
82.1
N.A.
61
64.4
N.A.
64
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
73.3
46.6
40
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
26.6
80
60
60
N.A.
20
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
89.9
N.A.
28.4
N.A.
N.A.
Protein Similarity:
N.A.
95.2
N.A.
45
N.A.
N.A.
P-Site Identity:
N.A.
100
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
60
0
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
14
7
0
7
7
0
14
0
0
0
14
20
0
7
7
% E
% Phe:
0
20
7
0
0
7
0
0
0
67
7
0
0
0
0
% F
% Gly:
7
0
0
0
7
0
0
0
27
0
60
0
0
67
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
7
7
14
7
0
0
7
0
7
0
0
7
0
0
% I
% Lys:
7
0
0
14
67
0
14
7
7
7
7
0
14
7
67
% K
% Leu:
20
20
7
54
0
7
0
7
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
7
% M
% Asn:
0
0
0
0
0
0
14
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
80
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
0
0
7
0
40
0
0
7
7
54
0
0
14
% S
% Thr:
0
0
14
0
0
0
7
0
7
7
0
7
14
7
0
% T
% Val:
7
40
7
7
0
7
0
0
0
7
7
0
40
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
54
7
0
0
0
67
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _